Standard
Hemoglobin
TRAFD1 · rs11065987
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hemoglobin compared to the general population. (GWAS Catalog, Nat Genet 2009, PMID:19862010)
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hemoglobin. (GWAS Catalog, Nat Genet 2009, PMID:19862010)
G/G
Published research associates this genotype with typical/baseline likelihood of Hemoglobin — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2009, PMID:19862010)
Source
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
Ganesh SK,
Zakai NA,
van Rooij FJ,
Soranzo N,
Smith AV,
Nalls MA,
Chen MH,
Kottgen A,
Glazer NL,
Dehghan A,
Kuhnel B,
Aspelund T
and 50 more — show all
Yang Q,
Tanaka T,
Jaffe A,
Bis JC,
Verwoert GC,
Teumer A,
Fox CS,
Guralnik JM,
Ehret GB,
Rice K,
Felix JF,
Rendon A,
Eiriksdottir G,
Levy D,
Patel KV,
Boerwinkle E,
Rotter JI,
Hofman A,
Sambrook JG,
Hernandez DG,
Zheng G,
Bandinelli S,
Singleton AB,
Coresh J,
Lumley T,
Uitterlinden AG,
Vangils JM,
Launer LJ,
Cupples LA,
Oostra BA,
Zwaginga JJ,
Ouwehand WH,
Thein SL,
Meisinger C,
Deloukas P,
Nauck M,
Spector TD,
Gieger C,
Gudnason V,
van Duijn CM,
Psaty BM,
Ferrucci L,
Chakravarti A,
Greinacher A,
O'Donnell CJ,
Witteman JC,
Furth S,
Cushman M,
Harris TB,
Lin JP
Nature genetics · 2009 · PMID 19862010 · open access
Questions about rs11065987
What is rs11065987?
rs11065987 is a single position in the genome, in or near the TRAFD1 gene. Published research associates it with hemoglobin. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11065987 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11065987 come from?
GWAS Catalog, Nat Genet 2009, PMID:19862010. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants