Standard

IGF 1 (UKB data field 30770)

WNK1 · rs11064536

Where this position leads

Condition: Celiac Disease

rs11064536 Condition: Celiac Disease Celiac Disease Condition rs11064536 rs11064536 WNK1

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0172 lower (95% confidence interval 0.012-0.022); p = 2 × 10−12.

How common The C allele had a frequency of about 17% in the people studied.

Where it sits Chromosome 12, band 12p13.33 — in an intron of WNK1.

What each result means

C/C Two copies of the version the research linked to IGF 1 (UKB data field 30770). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to IGF 1 (UKB data field 30770). That is a smaller link than two copies.
T/T No copy of the version the research linked to IGF 1 (UKB data field 30770). This is the starting point the study compared everyone against.
Source

Questions about rs11064536

What is rs11064536?

rs11064536 is a single position in the genome, in or near the WNK1 gene. Published research associates it with igf 1 (ukb data field 30770). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11064536 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs11064536 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11064536 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

IGF 1 (UKB data field 30770) (rs11064536). MyGeneLog™. https://www.mygenelog.com/variants/rs11064536

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