Sensitive

Systemic lupus erythematosus

SLC15A4 · rs11059919

Where this position leads

Condition: Systemic Lupus Erythematosus

rs11059919 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs11059919 rs11059919 SLC15A4

What the study found

Who was studied 5,201 European ancestry cases, 9,066 European ancestry controls.

The effect Each copy of the G allele carried 1.16 times the odds of Systemic lupus erythematosus; p = 8 × 10−9.

Where it sits Chromosome 12, band 12q24.33 — in an intron of SLC15A4.

What each result means

A/A No copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11059919

What is rs11059919?

rs11059919 is a single position in the genome, in or near the SLC15A4 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11059919 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

Does having rs11059919 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11059919 come from?

GWAS Catalog, Nat Genet 2015, PMID:26502338. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systemic lupus erythematosus (rs11059919). MyGeneLog™. https://www.mygenelog.com/variants/rs11059919

← See all variants