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Who was studied 15,704 European ancestry cases, 378,169 European ancestry controls.
The effect
Each copy of the T allele carried 1.08 times the odds of Osteoarthritis (hip) (95% confidence interval 1.05-1.1); p = 7 × 10−11.
How common The T allele had a frequency of about 48% in the people studied.
Where it sits Chromosome 12, band 12q24.31 — in an intron of MLXIP.
What each result means
C/CNo copy of the version the research linked to Osteoarthritis (hip). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Osteoarthritis (hip). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Osteoarthritis (hip). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2019 · PMID 30664745 · open access
Questions about rs11059094
What is rs11059094?
rs11059094 is a single position in the genome, in or near the MLXIP gene. Published research associates it with osteoarthritis (hip). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11059094 linked to?
On MyGeneLog this position is linked to Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs11059094 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11059094 come from?
GWAS Catalog, Nature genetics 2019, PMID:30664745. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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