C/CPublished research associates this genotype with typical/baseline likelihood of Waist-hip ratio — no copies of the reported risk allele.
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Waist-hip ratio.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Waist-hip ratio compared to the general population.
rs1105881 is a single position in the genome, in or near the MAPKBP1 gene. Published research associates it with waist-hip ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1105881 linked to?
On MyGeneLog this position is linked to Waist-to-Hip Ratio (Body Fat Distribution). The research behind each link, and its sources, are set out on that condition page.
Does having rs1105881 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1105881 come from?
GWAS Catalog, JAMA 2018, PMID:30575882. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.