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Lipoprotein-associated phospholipase A2 activity and mass

SCARB1 · rs11057841

What the study found

Who was studied 6,851 European ancestry individuals; replicated in 13,664 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0286 ng/ml higher (95% confidence interval 0.019-0.038); p = 6 × 10−14.

How common The T allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 12, band 12q24.31 — in an intron of SCARB1.

What each result means

C/C No copy of the version the research linked to Lipoprotein-associated phospholipase A2 activity and mass. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Lipoprotein-associated phospholipase A2 activity and mass. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Lipoprotein-associated phospholipase A2 activity and mass. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11057841

What is rs11057841?

rs11057841 is a single position in the genome, in or near the SCARB1 gene. Published research associates it with lipoprotein-associated phospholipase a2 activity and mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11057841 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11057841 come from?

GWAS Catalog, Circ Cardiovasc Genet 2012, PMID:23118302. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lipoprotein-associated phospholipase A2 activity and mass (rs11057841). MyGeneLog™. https://www.mygenelog.com/variants/rs11057841

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