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Vitamin E levels

SCARB1 · rs11057830

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 2,402 European ancestry cases, 1612 European ancestry controls; replicated in 475 European ancestry cases, 517 European ancestry controls, 1,416 cases, 1,359 controls.

The effect Each copy of the A allele shifted the measure 0.03 higher (95% confidence interval 0.01-0.05); p = 8 × 10⁻⁹.

How common The A allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 12, band 12q24.31 — in an intron of SCARB1.

What each result means

A/A Two copies of the version the research linked to Vitamin E levels. That is the strongest link of the three results. A link in a study is not a diagnosis.

A/G One copy of the version the research linked to Vitamin E levels. That is a smaller link than two copies.

G/G No copy of the version the research linked to Vitamin E levels. This is the starting point the study compared everyone against.

Source

Genome-wide association study identifies common variants associated with circulating vitamin E levels

Major JM, Yu K, Wheeler W, Zhang H, Cornelis MC, Wright ME, Yeager M, Snyder K, Weinstein SJ, Mondul A, Eliassen H, Purdue M

and 8 more — show all

Hazra A, McCarty CA, Hendrickson S, Virtamo J, Hunter D, Chanock S, Kraft P, Albanes D

Human molecular genetics · 2011 · PMID 21729881 · open access

What people read about alongside this

Vitamins and nutrient levels2 Heart and circulation1 Infection and immunity1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs11057830

What is rs11057830?

rs11057830 is a single position in the genome, in or near the SCARB1 gene. Published research associates it with vitamin e levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs11057830?

Subjects that appear in the title or abstract of the same papers as this rsID include vitamins and nutrient levels (2 papers), heart and circulation (1 papers), infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs11057830 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11057830 come from?

GWAS Catalog, Hum Mol Genet 2011, PMID:21729881. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Vitamin E levels (rs11057830). MyGeneLog™. https://www.mygenelog.com/variants/rs11057830

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