Standard

Metabolite levels

SLCO1B1 · rs11045879

Where this position leads

Condition: Blood Metabolite Levels

Drugs: Statins, Ticagrelor

rs11045879 Condition: Blood Metabolite Levels Blood Metabolite Levels Condition Drug: Statins Statins Drug Drug: Ticagrelor Ticagrelor Drug rs11045879 rs11045879 SLCO1B1

What the study found

Who was studied 214 European ancestry prostate cancer cases, 188 European ancestry controls; replicated in 489 European ancestry prostate cancer cases.

The effect The reported allele is C; the catalogue records no effect size ; p = 5 × 10−15.

Where it sits Chromosome 12, band 12p12.1 — in an intron of SLCO1B1.

What each result means

C/C Two copies of the version the research linked to Metabolite levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Metabolite levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Metabolite levels. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs11045879

What is rs11045879?

rs11045879 is a single position in the genome, in or near the SLCO1B1 gene. Published research associates it with metabolite levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11045879 linked to?

On MyGeneLog this position is linked to Blood Metabolite Levels. The research behind each link, and its sources, are set out on that condition page.

Does rs11045879 affect how medicines work?

SLCO1B1 carries pharmacogenomic findings for Statins, Ticagrelor. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

What do people read about alongside rs11045879?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs11045879 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11045879 come from?

GWAS Catalog, Hum Mutat 2013, PMID:23281178. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Metabolite levels (rs11045879). MyGeneLog™. https://www.mygenelog.com/variants/rs11045879

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