Standard
Ossification of the posterior longitudinal ligament of the spine
LOC100506393 · rs11045000
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Ossification of the posterior longitudinal ligament of the spine compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Ossification of the posterior longitudinal ligament of the spine.
G/G
Published research associates this genotype with typical/baseline likelihood of Ossification of the posterior longitudinal ligament of the spine — no copies of the reported risk allele.
Source
A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine
Nakajima M,
Takahashi A,
Tsuji T,
Karasugi T,
Baba H,
Uchida K,
Kawabata S,
Okawa A,
Shindo S,
Takeuchi K,
Taniguchi Y,
Maeda S
and 22 more — show all
Kashii M,
Seichi A,
Nakajima H,
Kawaguchi Y,
Fujibayashi S,
Takahata M,
Tanaka T,
Watanabe K,
Kida K,
Kanchiku T,
Ito Z,
Mori K,
Kaito T,
Kobayashi S,
Yamada K,
Takahashi M,
Chiba K,
Matsumoto M,
Furukawa K,
Kubo M,
Toyama Y,
Ikegawa S
Nature genetics · 2014 · PMID 25064007
Questions about rs11045000
What is rs11045000?
rs11045000 is a single position in the genome, in or near the LOC100506393 gene. Published research associates it with ossification of the posterior longitudinal ligament of the spine. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11045000 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11045000 come from?
GWAS Catalog, Nat Genet 2014, PMID:25064007. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants