Ossification of the posterior longitudinal ligament of the spine
LOC100506393 · rs11045000
0 2832515237Reads by AI crawlersClaude3ChatGPT2Google · Gemini5Perplexity1Meta AI5Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others7Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,112 Japanese ancestry cases, 6,810 Japanese ancestry controls; replicated in 548 Japanese ancestry cases, 6,469 Japanese ancestry controls.
The effect
Each copy of the A allele carried 1.28 times the odds of Ossification of the posterior longitudinal ligament of the spine (95% confidence interval 1.19-1.38); p = 3 × 10−11.
How common The A allele had a frequency of about 46% in the people studied.
Where it sits Chromosome 12, band 12p12.2 — in an intron of LINC02398.
What each result means
A/ATwo copies of the version the research linked to Ossification of the posterior longitudinal ligament of the spine. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Ossification of the posterior longitudinal ligament of the spine. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Ossification of the posterior longitudinal ligament of the spine. This is the starting point the study compared everyone against.
rs11045000 is a single position in the genome, in or near the LOC100506393 gene. Published research associates it with ossification of the posterior longitudinal ligament of the spine. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11045000 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11045000 come from?
GWAS Catalog, Nat Genet 2014, PMID:25064007. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2832515237Reads by AI crawlersClaude3ChatGPT2Google · Gemini5Perplexity1Meta AI5Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others7Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Ossification of the posterior longitudinal ligament of the spine (rs11045000). MyGeneLog™. https://www.mygenelog.com/variants/rs11045000