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Who was studied 797 European ancestry cases, 140,558 European ancestry controls; replicated in 2,812 European ancestry cases, 229,788 European ancestry controls.
The effect
Each copy of the A allele carried 1.24 times the odds of Polycystic ovary syndrome (adjusted for age) (95% confidence interval 1.15–1.34] ); p = 9 × 10−9.
How common The A allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 11, band 11p14.1 — in an intron of ARL14EP-DT.
What each result means
A/ATwo copies of the version the research linked to Polycystic ovary syndrome (adjusted for age). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Polycystic ovary syndrome (adjusted for age). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Polycystic ovary syndrome (adjusted for age). This is the starting point the study compared everyone against.
Human reproduction (Oxford, England) · 2022 · PMID 34791234 · open access
Questions about rs11031002
What is rs11031002?
rs11031002 is a single position in the genome, in or near the FSHB gene. Published research associates it with polycystic ovary syndrome (adjusted for age). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11031002 linked to?
On MyGeneLog this position is linked to Polycystic Ovary Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does having rs11031002 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11031002 come from?
GWAS Catalog, Hum Reprod 2021, PMID:34791234. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 36128123118Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity2Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others18Total36Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Polycystic ovary syndrome (adjusted for age) (rs11031002). MyGeneLog™. https://www.mygenelog.com/variants/rs11031002