Standard

systolic blood pressure (SBP, mean, inv-normal transformed)

METTL15 · rs11030306

Where this position leads

Condition: Blood Pressure

rs11030306 Condition: Blood Pressure Blood Pressure Condition rs11030306 rs11030306 METTL15

What the study found

Who was studied 119,331 African American or Afro-Caribbean individuals, 57,988 Hispanic or Latin American individuals, 6,420 East Asian ancestry individuals, 425,740 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0192 higher (95% confidence interval 0.014-0.025); p = 3 × 10−11.

How common The C allele had a frequency of about 56% in the people studied.

Where it sits Chromosome 11, band 11p14.1 — inside METTL15.

What each result means

C/C Two copies of the version the research linked to systolic blood pressure (SBP, mean, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to systolic blood pressure (SBP, mean, inv-normal transformed). That is a smaller link than two copies.
T/T No copy of the version the research linked to systolic blood pressure (SBP, mean, inv-normal transformed). This is the starting point the study compared everyone against.
Source

Questions about rs11030306

What is rs11030306?

rs11030306 is a single position in the genome, in or near the METTL15 gene. Published research associates it with systolic blood pressure (sbp, mean, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11030306 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs11030306 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11030306 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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systolic blood pressure (SBP, mean, inv-normal transformed) (rs11030306). MyGeneLog™. https://www.mygenelog.com/variants/rs11030306

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