Standard
Mean arterial pressure
CACNB2 · rs11014166
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Mean arterial pressure — no copies of the reported risk allele.
A/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Mean arterial pressure.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Mean arterial pressure compared to the general population.
Source
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci
Liu C,
Kraja AT,
Smith JA,
Brody JA,
Franceschini N,
Bis JC,
Rice K,
Morrison AC,
Lu Y,
Weiss S,
Guo X,
Palmas W
and 83 more — show all
Martin LW,
Chen YD,
Surendran P,
Drenos F,
Cook JP,
Auer PL,
Chu AY,
Giri A,
Zhao W,
Jakobsdottir J,
Lin LA,
Stafford JM,
Amin N,
Mei H,
Yao J,
Voorman A,
Larson MG,
Grove ML,
Smith AV,
Hwang SJ,
Chen H,
Huan T,
Kosova G,
Stitziel NO,
Kathiresan S,
Samani N,
Schunkert H,
Deloukas P,
Li M,
Fuchsberger C,
Pattaro C,
Gorski M,
Kooperberg C,
Papanicolaou GJ,
Rossouw JE,
Faul JD,
Kardia SL,
Bouchard C,
Raffel LJ,
Uitterlinden AG,
Franco OH,
Vasan RS,
O'Donnell CJ,
Taylor KD,
Liu K,
Bottinger EP,
Gottesman O,
Daw EW,
Giulianini F,
Ganesh S,
Salfati E,
Harris TB,
Launer LJ,
Dörr M,
Felix SB,
Rettig R,
Völzke H,
Kim E,
Lee WJ,
Lee IT,
Sheu WH,
Tsosie KS,
Edwards DR,
Liu Y,
Correa A,
Weir DR,
Völker U,
Ridker PM,
Boerwinkle E,
Gudnason V,
Reiner AP,
van Duijn CM,
Borecki IB,
Edwards TL,
Chakravarti A,
Rotter JI,
Psaty BM,
Loos RJ,
Fornage M,
Ehret GB,
Newton-Cheh C,
Levy D,
Chasman DI
Nature genetics · 2016 · PMID 27618448
Questions about rs11014166
What is rs11014166?
rs11014166 is a single position in the genome, in or near the CACNB2 gene. Published research associates it with mean arterial pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11014166 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11014166 come from?
GWAS Catalog, Nat Genet 2016, PMID:27618448. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants