Sensitive

Breast cancer

SKIDA1 · rs11012730

Where this position leads

Condition: Breast Cancer

rs11012730 Condition: Breast Cancer Breast Cancer Condition rs11012730 rs11012730 SKIDA1

What the study found

Who was studied 17,389 European ancestry cases, 240,341 European ancestry controls, 6,325 East Asian ancestry cases, 73,225 East Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0747 higher (95% confidence interval 0.052-0.098); p = 3 × 10−10.

Where it sits Chromosome 10, band 10p12.31 — in an intron of SKIDA1.

What each result means

A/A Two copies of the version the research linked to Breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Breast cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to Breast cancer. This is the starting point the study compared everyone against.
Source

Questions about rs11012730

What is rs11012730?

rs11012730 is a single position in the genome, in or near the SKIDA1 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11012730 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs11012730 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11012730 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Breast cancer (rs11012730). MyGeneLog™. https://www.mygenelog.com/variants/rs11012730

← See all variants