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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 437,438 European ancestry individuals; replicated in 315,572 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0016 lower (95% confidence interval 0.0011-0.0021); p = 4 × 10−11.
How common The T allele had a frequency of about 72% in the people studied.
Where it sits Chromosome 10, band 10p12.1 — between genes, 4.9 kb from WAC.
What each result means
C/CNo copy of the version the research linked to Liver enzyme levels (alkaline phosphatase). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Liver enzyme levels (alkaline phosphatase). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Liver enzyme levels (alkaline phosphatase). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2021 · PMID 33972514 · open access
Questions about rs11007165
What is rs11007165?
rs11007165 is a single position in the genome, in or near the WAC gene. Published research associates it with liver enzyme levels (alkaline phosphatase). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11007165 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11007165 come from?
GWAS Catalog, Nature communications 2021, PMID:33972514. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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