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Mitochondrial DNA levels

TFAM · rs11006132

What the study found

Who was studied 295,150 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.031 higher (95% confidence interval 0.025-0.037); p = 4 × 10−24.

How common The G allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 10, band 10q21.1 — in the 3′ untranslated region of TFAM.

What each result means

A/A No copy of the version the research linked to Mitochondrial DNA levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Mitochondrial DNA levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Mitochondrial DNA levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11006132

What is rs11006132?

rs11006132 is a single position in the genome, in or near the TFAM gene. Published research associates it with mitochondrial dna levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11006132 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11006132 come from?

GWAS Catalog, Human genetics 2021, PMID:33385171. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mitochondrial DNA levels (rs11006132). MyGeneLog™. https://www.mygenelog.com/variants/rs11006132

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