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Pulse pressure

VCL · rs11000852

What the study found

Who was studied 360,863 European ancestry individuals, 145,445 East Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0184 lower (95% confidence interval 0.014-0.023); p = 8 × 10−18.

Where it sits Chromosome 10, band 10q22.2 — in an intron of VCL.

What each result means

C/C Two copies of the version the research linked to Pulse pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Pulse pressure. That is a smaller link than two copies.
T/T No copy of the version the research linked to Pulse pressure. This is the starting point the study compared everyone against.
Source

Questions about rs11000852

What is rs11000852?

rs11000852 is a single position in the genome, in or near the VCL gene. Published research associates it with pulse pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11000852 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11000852 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Pulse pressure (rs11000852). MyGeneLog™. https://www.mygenelog.com/variants/rs11000852

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