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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 10,600 European ancestry cases, 181,898 European ancestry controls.
The effect
Each copy of the A allele carried 0.93 times the odds of Sciatica (95% confidence interval 0.9-0.95); p = 5 × 10−8.
Where it sits Chromosome 10, band 10q22.1 — in an intron of ASCC1.
What each result means
A/ATwo copies of the version the research linked to Sciatica. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Sciatica. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Sciatica. This is the starting point the study compared everyone against.
rs11000202 is a single position in the genome, in or near the ASCC1 gene. Published research associates it with sciatica. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11000202 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11000202 come from?
GWAS Catalog, Pain 2026, PMID:40899795. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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