Standard

Percent mammographic density

near ZNF365 · rs10995187

What the study found

Who was studied 27,900 European ancestry females.

The effect Each copy of the G allele shifted the measure 1.92 z score higher; p = 2 × 10−25.

How common The G allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 10, band 10q21.2 — between genes, 7.2 kb from LINC02929.

What each result means

A/A No copy of the version the research linked to Percent mammographic density. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Percent mammographic density. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Percent mammographic density. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10995187

What is rs10995187?

rs10995187 is a single position in the genome, in or near the near ZNF365 gene. Published research associates it with percent mammographic density. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10995187 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10995187 come from?

GWAS Catalog, Breast cancer research : BCR 2022, PMID:35414113. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Percent mammographic density (rs10995187). MyGeneLog™. https://www.mygenelog.com/variants/rs10995187

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