C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) compared to the general population. (GWAS Catalog, Lancet 2013, PMID:23453885)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined). (GWAS Catalog, Lancet 2013, PMID:23453885)
T/TPublished research associates this genotype with typical/baseline likelihood of Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) — no copies of the reported risk allele. (GWAS Catalog, Lancet 2013, PMID:23453885)
Source: GWAS Catalog, Lancet 2013, PMID:23453885
Questions about rs10994359
What is rs10994359?
rs10994359 is a single position in the genome, in or near the ANK3 gene. Published research associates it with autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10994359 linked to?
On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs10994359 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10994359 come from?
GWAS Catalog, Lancet 2013, PMID:23453885. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.