Standard

3-indoleglyoxylic acid levels

near ENDOG · rs10988130

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 7,848 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.233 lower (95% confidence interval 0.2-0.27); p = 1 × 10⁻³⁸.

How common The G allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 9, band 9q34.11 — between genes, 1.2 kb from ENDOG.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of 3-indoleglyoxylic acid levels — no copies of the reported risk allele.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with 3-indoleglyoxylic acid levels.

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of 3-indoleglyoxylic acid levels compared to the general population.

Source

Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases

Chen Y, Lu T, Pettersson-Kymmer U, Stewart ID, Butler-Laporte G, Nakanishi T, Cerani A, Liang KYH, Yoshiji S, Willett JDS, Su CY, Raina P

and 7 more — show all

Greenwood CMT, Farjoun Y, Forgetta V, Langenberg C, Zhou S, Ohlsson C, Richards JB

Nature genetics · 2023 · PMID 36635386

Questions about rs10988130

What is rs10988130?

rs10988130 is a single position in the genome, in or near the near ENDOG gene. Published research associates it with 3-indoleglyoxylic acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10988130 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10988130 come from?

GWAS Catalog, Nature genetics 2023, PMID:36635386. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

3-indoleglyoxylic acid levels (rs10988130). MyGeneLog™. https://www.mygenelog.com/variants/rs10988130

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