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Who was studied 1,423 Japanese ancestry cases, 1,318 Japanese ancestry controls; replicated in 484 Japanese ancestry cases, 3,974 Japanese ancestry controls.
The effect
Each copy of the C allele carried 1.44 times the odds of Endometriosis (95% confidence interval 1.30-1.59); p = 6 × 10−12.
How common The C allele had a frequency of about 80% in the people studied.
Where it sits Chromosome 9, band 9p21.3 — in an intron of CDKN2B-AS1.
What each result means
A/ANo copy of the version the research linked to Endometriosis. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Endometriosis. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Endometriosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs10965235 is a single position in the genome, in or near the CDKN2BAS gene. Published research associates it with endometriosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10965235 linked to?
On MyGeneLog this position is linked to Endometriosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs10965235 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10965235 come from?
GWAS Catalog, Nature genetics 2010, PMID:20601957. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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