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Hair color

TYRP1 · rs10960765

Where this position leads

Condition: Hair Color

rs10960765 Condition: Hair Color Hair Color Condition rs10960765 rs10960765 TYRP1

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Hair color — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hair color.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hair color compared to the general population.
Source
Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability
Hysi PG, Valdes AM, Liu F, Furlotte NA, Evans DM, Bataille V, Visconti A, Hemani G, McMahon G, Ring SM, Smith GD, Duffy DL
and 32 more — show all
Zhu G, Gordon SD, Medland SE, Lin BD, Willemsen G, Jan Hottenga J, Vuckovic D, Girotto G, Gandin I, Sala C, Concas MP, Brumat M, Gasparini P, Toniolo D, Cocca M, Robino A, Yazar S, Hewitt AW, Chen Y, Zeng C, Uitterlinden AG, Ikram MA, Hamer MA, van Duijn CM, Nijsten T, Mackey DA, Falchi M, Boomsma DI, Martin NG, Hinds DA, Kayser M, Spector TD
International Visible Trait Genetics Consortium
Nature genetics · 2018 · PMID 29662168 · open access

Questions about rs10960765

What is rs10960765?

rs10960765 is a single position in the genome, in or near the TYRP1 gene. Published research associates it with hair color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10960765 linked to?

On MyGeneLog this position is linked to Hair Color. The research behind each link, and its sources, are set out on that condition page.

Does having rs10960765 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10960765 come from?

GWAS Catalog, Nat Genet 2018, PMID:29662168. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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