Standard

Low density lipoprotein cholesterol levels

near UBXN2B · rs10957055

Where this position leads

Condition: Gout

rs10957055 Condition: Gout Gout Condition rs10957055 rs10957055 near UBXN2B

What the study found

Who was studied 341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0266 higher (95% confidence interval 0.018-0.035); p = 1 × 10−9.

Where it sits Chromosome 8, band 8q12.1 — between genes, 1.5 kb from UBXN2B.

What each result means

C/C No copy of the version the research linked to Low density lipoprotein cholesterol levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Low density lipoprotein cholesterol levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Low density lipoprotein cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10957055

What is rs10957055?

rs10957055 is a single position in the genome, in or near the near UBXN2B gene. Published research associates it with low density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10957055 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs10957055 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10957055 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Low density lipoprotein cholesterol levels (rs10957055). MyGeneLog™. https://www.mygenelog.com/variants/rs10957055

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