Sensitive

Neuropathic pain in head and neck cancer

SNX8 · rs10950641

What the study found

Who was studied 130 European ancestry cases, 913 European ancestry controls.

The effect Each copy of the A allele carried 2.88 times the odds of Neuropathic pain in head and neck cancer (95% confidence interval 2.19, 3.79); p = 3 × 10−14.

How common The A allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 7, band 7p22.3 — in an intron of SNX8.

What each result means

A/A Two copies of the version the research linked to Neuropathic pain in head and neck cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Neuropathic pain in head and neck cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to Neuropathic pain in head and neck cancer. This is the starting point the study compared everyone against.
Source

Questions about rs10950641

What is rs10950641?

rs10950641 is a single position in the genome, in or near the SNX8 gene. Published research associates it with neuropathic pain in head and neck cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10950641 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10950641 come from?

GWAS Catalog, Scientific reports 2018, PMID:29884837. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Neuropathic pain in head and neck cancer (rs10950641). MyGeneLog™. https://www.mygenelog.com/variants/rs10950641

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