Sensitive

Osteoarthritis (hip)

SUPT3H · rs10948172

Where this position leads

Condition: Osteoarthritis

rs10948172 Condition: Osteoarthritis Osteoarthritis Condition rs10948172 rs10948172 SUPT3H

What the study found

Who was studied 17,151 European ancestry cases, 596,639 European ancestry controls.

The effect Each copy of the G allele carried 1.09 times the odds of Osteoarthritis (hip); p = 9 × 10−11.

How common The G allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 6, band 6p21.1 — in an intron of SUPT3H.

What each result means

A/A No copy of the version the research linked to Osteoarthritis (hip). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Osteoarthritis (hip). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Osteoarthritis (hip). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10948172

What is rs10948172?

rs10948172 is a single position in the genome, in or near the SUPT3H gene. Published research associates it with osteoarthritis (hip). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10948172 linked to?

On MyGeneLog this position is linked to Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.

Does having rs10948172 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10948172 come from?

GWAS Catalog, Nature genetics 2018, PMID:30374069. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Osteoarthritis (hip) (rs10948172). MyGeneLog™. https://www.mygenelog.com/variants/rs10948172

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