Sensitive

Knee osteoarthritis

HLA-DQA2 · rs10947262

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Knee osteoarthritis — no copies of the reported risk allele. (GWAS Catalog, PLoS One 2010, PMID:20305777)

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Knee osteoarthritis. (GWAS Catalog, PLoS One 2010, PMID:20305777)

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Knee osteoarthritis compared to the general population. (GWAS Catalog, PLoS One 2010, PMID:20305777)

Source: GWAS Catalog, PLoS One 2010, PMID:20305777

Questions about rs10947262

What is rs10947262?

rs10947262 is a single position in the genome, in or near the HLA-DQA2 gene. Published research associates it with knee osteoarthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10947262 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10947262 come from?

GWAS Catalog, PLoS One 2010, PMID:20305777. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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