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Height

HIST1H1D · rs10946808

Where this position leads

Condition: Height

rs10946808 Condition: Height Height Condition rs10946808 rs10946808 HIST1H1D

What the study found

Who was studied 15,821 European ancestry individuals; replicated in Up to 17,801 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.36 cm lower (95% confidence interval 0.26-0.46); p = 4 × 10−17.

How common The G allele had a frequency of about 28% in the people studied.

Where it sits Chromosome 6, band 6p22.2 — in a non-coding transcript of H2AC9P.

What each result means

A/A No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Height. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10946808

What is rs10946808?

rs10946808 is a single position in the genome, in or near the HIST1H1D gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10946808 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs10946808 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10946808 come from?

GWAS Catalog, Nat Genet 2008, PMID:18391950. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs10946808). MyGeneLog™. https://www.mygenelog.com/variants/rs10946808

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