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Whole body fat mass (UKB data field 23100)

near H2BC4 · rs10946805

What the study found

Who was studied 337,196 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0222 lower (95% confidence interval 0.017-0.028); p = 1 × 10−15.

Where it sits Chromosome 6, band 6p22.2 — between genes, 8.7 kb from H2BC4.

What each result means

C/C No copy of the version the research linked to Whole body fat mass (UKB data field 23100). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Whole body fat mass (UKB data field 23100). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Whole body fat mass (UKB data field 23100). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10946805

What is rs10946805?

rs10946805 is a single position in the genome, in or near the near H2BC4 gene. Published research associates it with whole body fat mass (ukb data field 23100). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10946805 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10946805 come from?

GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Whole body fat mass (UKB data field 23100) (rs10946805). MyGeneLog™. https://www.mygenelog.com/variants/rs10946805

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