A/APublished research associates this genotype with typical/baseline likelihood of Angiotensin-converting enzyme inhibitor intolerance — no copies of the reported risk allele.
A/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Angiotensin-converting enzyme inhibitor intolerance.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Angiotensin-converting enzyme inhibitor intolerance compared to the general population.
Pharmacogenetics and genomics · 2017 · PMID 28030426
Questions about rs10946364
What is rs10946364?
rs10946364 is a single position in the genome, in or near the MBOAT1 gene. Published research associates it with angiotensin-converting enzyme inhibitor intolerance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10946364 linked to?
On MyGeneLog this position is linked to ACE Inhibitor Intolerance. The research behind each link, and its sources, are set out on that condition page.
Does having rs10946364 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10946364 come from?
GWAS Catalog, Pharmacogenet Genomics 2017, PMID:28030426. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.