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Glycine levels

ALDH1L1 · rs10934754

What the study found

Who was studied 117,944 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0701 lower (95% confidence interval 0.063-0.078); p = 5 × 10−88.

How common The T allele had a frequency of about 59% in the people studied.

Where it sits Chromosome 3, band 3q21.3 — in an intron of ALDH1L1.

What each result means

C/C No copy of the version the research linked to Glycine levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Glycine levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Glycine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10934754

What is rs10934754?

rs10934754 is a single position in the genome, in or near the ALDH1L1 gene. Published research associates it with glycine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10934754 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10934754 come from?

GWAS Catalog, NAR genomics and bioinformatics 2024, PMID:38711861. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Glycine levels (rs10934754). MyGeneLog™. https://www.mygenelog.com/variants/rs10934754

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