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Eosinophil count

NOSTRIN · rs10930337

Where this position leads

Condition: Blood Cell Counts

rs10930337 Condition: Blood Cell Counts Blood Cell Counts Condition rs10930337 rs10930337 NOSTRIN

What the study found

Who was studied 474,237 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0147 SD unit higher (95% confidence interval 0.01-0.019); p = 2 × 10−11.

How common The T allele had a frequency of about 28% in the people studied.

Where it sits Chromosome 2, band 2q24.3 — in an intron of NOSTRIN.

What each result means

C/C No copy of the version the research linked to Eosinophil count. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Eosinophil count. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Eosinophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10930337

What is rs10930337?

rs10930337 is a single position in the genome, in or near the NOSTRIN gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10930337 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs10930337 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10930337 come from?

GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Eosinophil count (rs10930337). MyGeneLog™. https://www.mygenelog.com/variants/rs10930337

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