Standard

Dilated cardiomyopathy

ZBTB17 · rs10927875

Where this position leads

Condition: Dilated Cardiomyopathy

rs10927875 Condition: Dilated Cardiomyopathy Dilated Cardiomyopathy Condition rs10927875 rs10927875 ZBTB17

What the study found

Who was studied 5,521 cases, 397,323 controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 6 × 10−18.

How common The C allele had a frequency of about 67% in the people studied.

Where it sits Chromosome 1, band 1p36.13 — in an intron of ZBTB17.

What each result means

C/C Two copies of the version the research linked to Dilated cardiomyopathy. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Dilated cardiomyopathy. That is a smaller link than two copies.
T/T No copy of the version the research linked to Dilated cardiomyopathy. This is the starting point the study compared everyone against.
Source

Questions about rs10927875

What is rs10927875?

rs10927875 is a single position in the genome, in or near the ZBTB17 gene. Published research associates it with dilated cardiomyopathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10927875 linked to?

On MyGeneLog this position is linked to Dilated Cardiomyopathy. The research behind each link, and its sources, are set out on that condition page.

Does having rs10927875 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10927875 come from?

GWAS Catalog, Nature genetics 2021, PMID:33495596. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Dilated cardiomyopathy (rs10927875). MyGeneLog™. https://www.mygenelog.com/variants/rs10927875

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