Standard

diastolic blood pressure (DBP, mean, inv-normal transformed)

SDCCAG8 · rs10926989

Where this position leads

Condition: Blood Pressure

rs10926989 Condition: Blood Pressure Blood Pressure Condition rs10926989 rs10926989 SDCCAG8

What the study found

Who was studied 119,332 African American or Afro-Caribbean individuals, 57,990 Hispanic or Latin American individuals, 6,421 East Asian ancestry individuals, 425,743 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.032 lower (95% confidence interval 0.026-0.038); p = 1 × 10−27.

How common The C allele had a frequency of about 73% in the people studied.

Where it sits Chromosome 1, band 1q43 — in an intron of SDCCAG8.

What each result means

C/C Two copies of the version the research linked to diastolic blood pressure (DBP, mean, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to diastolic blood pressure (DBP, mean, inv-normal transformed). That is a smaller link than two copies.
T/T No copy of the version the research linked to diastolic blood pressure (DBP, mean, inv-normal transformed). This is the starting point the study compared everyone against.
Source

Questions about rs10926989

What is rs10926989?

rs10926989 is a single position in the genome, in or near the SDCCAG8 gene. Published research associates it with diastolic blood pressure (dbp, mean, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10926989 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs10926989 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10926989 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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diastolic blood pressure (DBP, mean, inv-normal transformed) (rs10926989). MyGeneLog™. https://www.mygenelog.com/variants/rs10926989

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