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Placental weight (fetal genotype, adjusted for sex)

CHRM3 · rs10925945

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 65,651 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0693 higher (95% confidence interval 0.047-0.091); p = 9 × 10⁻¹⁰.

How common The T allele had a frequency of about 94% in the people studied.

Where it sits Chromosome 1, band 1q43 — in an intron of CHRM3.

What each result means

C/C No copy of the version the research linked to Placental weight (fetal genotype, adjusted for sex). This is the starting point the study compared everyone against.

C/T One copy of the version the research linked to Placental weight (fetal genotype, adjusted for sex). That is a smaller link than two copies.

T/T Two copies of the version the research linked to Placental weight (fetal genotype, adjusted for sex). That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

Beaumont RN, Flatley C, Vaudel M, Wu X, Chen J, Moen GH, Skotte L, Helgeland Ø, Solé-Navais P, Banasik K, Albiñana C, Ronkainen J

and 76 more — show all

Fadista J, Stinson SE, Trajanoska K, Wang CA, Westergaard D, Srinivasan S, Sánchez-Soriano C, Bilbao JR, Allard C, Groleau M, Kuulasmaa T, Leirer DJ, White F, Jacques PÉ, Cheng H, Hao K, Andreassen OA, Åsvold BO, Atalay M, Bhatta L, Bouchard L, Brumpton BM, Brunak S, Bybjerg-Grauholm J, Ebbing C, Elliott P, Engelbrechtsen L, Erikstrup C, Estarlich M, Franks S, Gaillard R, Geller F, Grove J, Hougaard DM, Kajantie E, Morgen CS, Nohr EA, Nyegaard M, Palmer CNA, Pedersen OB, Rivadeneira F, Sebert S, Shields BM, Stoltenberg C, Surakka I, Thørner LW, Ullum H, Vaarasmaki M, Vilhjalmsson BJ, Willer CJ, Lakka TA, Gybel-Brask D, Bustamante M, Hansen T, Pearson ER, Reynolds RM, Ostrowski SR, Pennell CE, Jaddoe VWV, Felix JF, Hattersley AT, Melbye M, Lawlor DA, Hveem K, Werge T, Nielsen HS, Magnus P, Evans DM, Jacobsson B, Järvelin MR, Zhang G, Hivert MF, Johansson S, Freathy RM, Feenstra B, Njølstad PR

Early Growth Genetics (EGG) Consortium

Nature genetics · 2023 · PMID 37798380 · open access

Questions about rs10925945

What is rs10925945?

rs10925945 is a single position in the genome, in or near the CHRM3 gene. Published research associates it with placental weight (fetal genotype, adjusted for sex). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10925945 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10925945 come from?

GWAS Catalog, Nature genetics 2023, PMID:37798380. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Placental weight (fetal genotype, adjusted for sex) (rs10925945). MyGeneLog™. https://www.mygenelog.com/variants/rs10925945

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