0 453236213124Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity3Meta AI6Microsoft · Copilot2Amazon1Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others24Total45Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,100 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.521 higher (95% confidence interval 0.43-0.61); p = 2 × 10−30.
How common The C allele had a frequency of about 84% in the people studied.
Where it sits Chromosome 1, band 1q31.3 — a synonymous change in ASPM.
What ClinVar records
ClassificationBenign for Microcephaly 5, primary, autosomal recessive, Familial cancer of breast; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 13 submitters), last evaluated 2026-02-03.
ClinVar record 21603NM_018136.5(ASPM):c.7605G>A (p.Val2535=)
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CTwo copies of the version the research linked to End-stage coagulation. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to End-stage coagulation. That is a smaller link than two copies.
T/TNo copy of the version the research linked to End-stage coagulation. This is the starting point the study compared everyone against.
Annals of neurology · 2013 · PMID 23381943 · open access
Questions about rs10922162
What is rs10922162?
rs10922162 is a single position in the genome, in or near the CFHR4 gene. Published research associates it with end-stage coagulation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10922162 linked to?
On MyGeneLog this position is linked to Fibrinogen and Blood Clotting. The research behind each link, and its sources, are set out on that condition page.
Does having rs10922162 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10922162 come from?
GWAS Catalog, Ann Neurol 2013, PMID:23381943. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 453236213124Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity3Meta AI6Microsoft · Copilot2Amazon1Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others24Total45Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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