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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 416 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.449 lower (95% confidence interval 0.35-0.55); p = 3 × 10−16.
How common The T allele had a frequency of about 34% in the people studied.
Where it sits Chromosome 1, band 1q31.3 — in an intron of CFH.
What each result means
A/ANo copy of the version the research linked to Complement factor H-related protein 4A levels. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Complement factor H-related protein 4A levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Complement factor H-related protein 4A levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2021 · PMID 34260947 · open access
Questions about rs10922108
What is rs10922108?
rs10922108 is a single position in the genome, in or near the CFH gene. Published research associates it with complement factor h-related protein 4a levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10922108 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10922108 come from?
GWAS Catalog, American journal of human genetics 2021, PMID:34260947. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Complement factor H-related protein 4A levels (rs10922108). MyGeneLog™. https://www.mygenelog.com/variants/rs10922108