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Low affinity immunoglobulin gamma Fc region receptor III-B levels

near RPS23P10 · rs10919544

What the study found

Who was studied 997 European ancestry individuals; replicated in 338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.477 higher (95% confidence interval 0.39-0.56); p = 4 × 10−28.

Where it sits Chromosome 1, band 1q23.3 — between genes, 0.8 kb from RPS23P10.

What each result means

C/C Two copies of the version the research linked to Low affinity immunoglobulin gamma Fc region receptor III-B levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Low affinity immunoglobulin gamma Fc region receptor III-B levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Low affinity immunoglobulin gamma Fc region receptor III-B levels. This is the starting point the study compared everyone against.
Source

Questions about rs10919544

What is rs10919544?

rs10919544 is a single position in the genome, in or near the near RPS23P10 gene. Published research associates it with low affinity immunoglobulin gamma fc region receptor iii-b levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10919544 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10919544 come from?

GWAS Catalog, Nature communications 2017, PMID:28240269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Low affinity immunoglobulin gamma Fc region receptor III-B levels (rs10919544). MyGeneLog™. https://www.mygenelog.com/variants/rs10919544

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