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Takayasu arteritis

FCGR2A · rs10919543

Where this position leads

Condition: Takayasu Arteritis

rs10919543 Condition: Takayasu Arteritis Takayasu Arteritis Condition rs10919543 rs10919543 FCGR2A

What the study found

Who was studied 305 Turkish ancestry cases, 106 European ancestry cases, 483 Turkish ancestry controls, 553 European ancestry controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 6 × 10−12.

How common The G allele had a frequency of about 41% in the people studied.

Where it sits Chromosome 1, band 1q23.3 — between genes, 0.7 kb from RPS23P10.

What each result means

A/A No copy of the version the research linked to Takayasu arteritis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Takayasu arteritis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Takayasu arteritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10919543

What is rs10919543?

rs10919543 is a single position in the genome, in or near the FCGR2A gene. Published research associates it with takayasu arteritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10919543 linked to?

On MyGeneLog this position is linked to Takayasu Arteritis. The research behind each link, and its sources, are set out on that condition page.

Does having rs10919543 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10919543 come from?

GWAS Catalog, Am J Hum Genet 2013, PMID:23830517. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Takayasu arteritis (rs10919543). MyGeneLog™. https://www.mygenelog.com/variants/rs10919543

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