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QT interval

ATP1B1 · rs10919071

Where this position leads

Condition: QT Interval and Drug-Induced Long QT

rs10919071 Condition: QT Interval and Drug-Induced Long QT QT Interval and Drug-Induced Long QT Condition rs10919071 rs10919071 ATP1B1

What the study found

Who was studied 15,842 European ancestry individuals; replicated in up to 13,602 individuals.

The effect Each copy of the A allele shifted the measure 2.05 ms higher (95% confidence interval 1.48-2.62); p = 1 × 10−15.

How common The A allele had a frequency of about 87% in the people studied.

Where it sits Chromosome 1, band 1q24.2 — in an intron of ATP1B1.

What each result means

A/A Two copies of the version the research linked to QT interval. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to QT interval. That is a smaller link than two copies.
G/G No copy of the version the research linked to QT interval. This is the starting point the study compared everyone against.
Source

Questions about rs10919071

What is rs10919071?

rs10919071 is a single position in the genome, in or near the ATP1B1 gene. Published research associates it with qt interval. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10919071 linked to?

On MyGeneLog this position is linked to QT Interval and Drug-Induced Long QT. The research behind each link, and its sources, are set out on that condition page.

Does having rs10919071 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10919071 come from?

GWAS Catalog, Nat Genet 2009, PMID:19305409. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

QT interval (rs10919071). MyGeneLog™. https://www.mygenelog.com/variants/rs10919071

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