0 9126Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others6Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 9,207 European ancestry cases, 953,183 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.18 lower (95% confidence interval 0.15-0.21); p = 5 × 10−27.
How common The A allele had a frequency of about 54% in the people studied.
Where it sits Chromosome 1, band 1p36.13 — in an intron of OTUD3.
What each result means
A/ATwo copies of the version the research linked to Ulcerative colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Ulcerative colitis. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Ulcerative colitis. This is the starting point the study compared everyone against.
Life (Basel, Switzerland) · 2026 · PMID 42355477 · open access
Questions about rs10916666
What is rs10916666?
rs10916666 is a single position in the genome, in or near the OTUD3 gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10916666 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs10916666 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10916666 come from?
GWAS Catalog, Life (Basel, Switzerland) 2026, PMID:42355477. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 9126Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others6Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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