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Phospholipids to Total Lipids in Very Small VLDL percentage

TEX35 · rs10913568

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs10913568 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs10913568 rs10913568 TEX35

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the T allele shifted the measure 0.02 % higher (95% confidence interval 0.02-0.02); p = 4 × 10−15.

Where it sits Chromosome 1, band 1q25.2 — in an intron of C1orf220.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Phospholipids to Total Lipids in Very Small VLDL percentage — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Phospholipids to Total Lipids in Very Small VLDL percentage.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Phospholipids to Total Lipids in Very Small VLDL percentage compared to the general population.
Source

Questions about rs10913568

What is rs10913568?

rs10913568 is a single position in the genome, in or near the TEX35 gene. Published research associates it with phospholipids to total lipids in very small vldl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10913568 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs10913568 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10913568 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Phospholipids to Total Lipids in Very Small VLDL percentage (rs10913568). MyGeneLog™. https://www.mygenelog.com/variants/rs10913568

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