Sensitive

Urine S(2-carboxyethyl)mercapturic acid levels in chronic kidney disease

near SRP14P4 · rs10912836

What the study found

Who was studied 3,647 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.349 lower (95% confidence interval 0.29-0.41); p = 7 × 10−32.

How common The C allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 1, band 1q24.3 — between genes, 16.3 kb from SRP14P4.

What each result means

C/C Two copies of the version the research linked to Urine S(2-carboxyethyl)mercapturic acid levels in chronic kidney disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Urine S(2-carboxyethyl)mercapturic acid levels in chronic kidney disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Urine S(2-carboxyethyl)mercapturic acid levels in chronic kidney disease. This is the starting point the study compared everyone against.
Source

Questions about rs10912836

What is rs10912836?

rs10912836 is a single position in the genome, in or near the near SRP14P4 gene. Published research associates it with urine s(2-carboxyethyl)mercapturic acid levels in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10912836 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10912836 come from?

GWAS Catalog, Nature genetics 2023, PMID:37277652. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urine S(2-carboxyethyl)mercapturic acid levels in chronic kidney disease (rs10912836). MyGeneLog™. https://www.mygenelog.com/variants/rs10912836

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