4 5542129222229Reads by AI crawlersClaude4ChatGPT2Google · Gemini1Perplexity2Meta AI9Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others29Total55Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 36,948 European ancestry cases, 30,864 European ancestry controls; replicated in 12,952 European ancestry cases, 48,383 European ancestry controls, 8,580 East Asian ancestry cases, 13,050 East Asian ancestry controls, 1,611 Hispanic cases, 4,330 Hispanic controls, 1,894 African American cases, 4,703 African American controls.
The effect
Each copy of the A allele carried 1.07 times the odds of Colorectal cancer (95% confidence interval 1.04-1.10); p = 5 × 10−8.
How common The A allele had a frequency of about 55% in the people studied.
Where it sits Chromosome 1, band 1q25.3 — in an intron of LAMC1.
What each result means
A/ATwo copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs10911251
What is rs10911251?
rs10911251 is a single position in the genome, in or near the LAMC1 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10911251 linked to?
On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs10911251?
Subjects that appear in the title or abstract of the same papers as this rsID include alcohol and the flush (1 papers), infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs10911251 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10911251 come from?
GWAS Catalog, J Natl Cancer Inst 2018, PMID:29917119. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
4 5542129222229Reads by AI crawlersClaude4ChatGPT2Google · Gemini1Perplexity2Meta AI9Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others29Total55Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Colorectal cancer (rs10911251). MyGeneLog™. https://www.mygenelog.com/variants/rs10911251