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Serum 25-Hydroxyvitamin D levels (conditioned on BMI)

ASH1L · rs10908465

What the study found

Who was studied 417,580 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.017 higher (95% confidence interval 0.013-0.021); p = 5 × 10−14.

How common The C allele had a frequency of about 73% in the people studied.

Where it sits Chromosome 1, band 1q22 — in an intron of ASH1L.

What each result means

C/C Two copies of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). That is a smaller link than two copies.
T/T No copy of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). This is the starting point the study compared everyone against.
Source

Questions about rs10908465

What is rs10908465?

rs10908465 is a single position in the genome, in or near the ASH1L gene. Published research associates it with serum 25-hydroxyvitamin d levels (conditioned on bmi). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10908465 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10908465 come from?

GWAS Catalog, Nature communications 2020, PMID:32242144. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum 25-Hydroxyvitamin D levels (conditioned on BMI) (rs10908465). MyGeneLog™. https://www.mygenelog.com/variants/rs10908465

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