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Who was studied 100,453 Chinese Han ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.599 higher (95% confidence interval 0.4-0.79); p = 1 × 10−9.
How common The T allele had a frequency of about 66% in the people studied.
Where it sits Chromosome 10, band 10q11.21 — in an intron of TMEM72-AS1.
What each result means
C/CNo copy of the version the research linked to Systolic blood pressure (BMI adjusted). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Systolic blood pressure (BMI adjusted). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Systolic blood pressure (BMI adjusted). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39048560 · open access
Questions about rs10900130
What is rs10900130?
rs10900130 is a single position in the genome, in or near the TMEM72-AS1 gene. Published research associates it with systolic blood pressure (bmi adjusted). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10900130 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs10900130 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10900130 come from?
GWAS Catalog, Nature communications 2024, PMID:39048560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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