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Phosphatidylcholine acyl-alkyl C42:3 levels

UVRAG · rs10899134

What the study found

Who was studied 16,839 Caucasian ancestry individuals.

The effect Each copy of the G allele shifted the measure 6.67 (zscore) higher; p = 2 × 10−11.

How common The G allele had a frequency of about 91% in the people studied.

Where it sits Chromosome 11, band 11q13.5 — in an intron of UVRAG.

What each result means

C/C No copy of the version the research linked to Phosphatidylcholine acyl-alkyl C42:3 levels. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Phosphatidylcholine acyl-alkyl C42:3 levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Phosphatidylcholine acyl-alkyl C42:3 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10899134

What is rs10899134?

rs10899134 is a single position in the genome, in or near the UVRAG gene. Published research associates it with phosphatidylcholine acyl-alkyl c42:3 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10899134 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10899134 come from?

GWAS Catalog, Nature genetics 2021, PMID:33414548. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Phosphatidylcholine acyl-alkyl C42:3 levels (rs10899134). MyGeneLog™. https://www.mygenelog.com/variants/rs10899134

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