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C-reactive protein levels (MTAG)

near ATG16L2 · rs10898880

Where this position leads

Condition: C-Reactive Protein Levels

rs10898880 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs10898880 rs10898880 near ATG16L2

What the study found

Who was studied 575,531 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0149 lower (95% confidence interval 0.011-0.019); p = 2 × 10−13.

Where it sits Chromosome 11, band 11q13.4 — between genes, 0.1 kb from ATG16L2.

What each result means

A/A Two copies of the version the research linked to C-reactive protein levels (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to C-reactive protein levels (MTAG). That is a smaller link than two copies.
C/C No copy of the version the research linked to C-reactive protein levels (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs10898880

What is rs10898880?

rs10898880 is a single position in the genome, in or near the near ATG16L2 gene. Published research associates it with c-reactive protein levels (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10898880 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs10898880 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10898880 come from?

GWAS Catalog, Nature communications 2022, PMID:36376304. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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C-reactive protein levels (MTAG) (rs10898880). MyGeneLog™. https://www.mygenelog.com/variants/rs10898880

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