Gene Knowledge Graph
UTC
Sensitive

Prostate cancer

near SMIM38 · rs10896449

Where this position leads

Condition: Prostate Cancer

rs10896449 Condition: Prostate Cancer Prostate Cancer Condition rs10896449 rs10896449 near SMIM38

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Prostate cancer — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Prostate cancer.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Prostate cancer compared to the general population.
Source
A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences
Hoffmann TJ, Van Den Eeden SK, Sakoda LC, Jorgenson E, Habel LA, Graff RE, Passarelli MN, Cario CL, Emami NC, Chao CR, Ghai NR, Shan J
and 23 more — show all
Ranatunga DK, Quesenberry CP, Aaronson D, Presti J, Wang Z, Berndt SI, Chanock SJ, McDonnell SK, French AJ, Schaid DJ, Thibodeau SN, Li Q, Freedman ML, Penney KL, Mucci LA, Haiman CA, Henderson BE, Seminara D, Kvale MN, Kwok PY, Schaefer C, Risch N, Witte JS
Cancer discovery · 2015 · PMID 26034056

Questions about rs10896449

What is rs10896449?

rs10896449 is a single position in the genome, in or near the near SMIM38 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10896449 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs10896449 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10896449 come from?

GWAS Catalog, Cancer Discov 2015, PMID:26034056. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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