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Triacylglyceride levels

SIK3 · rs10892063

What the study found

Who was studied 22,000 Pakistani and Bangladeshi ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.08 lower (95% confidence interval 0.06-0.1); p = 1 × 10−8.

How common The C allele had a frequency of about 28% in the people studied.

Where it sits Chromosome 11, band 11q23.3 — in an intron of SIK3.

What each result means

A/A No copy of the version the research linked to Triacylglyceride levels. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Triacylglyceride levels. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Triacylglyceride levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10892063

What is rs10892063?

rs10892063 is a single position in the genome, in or near the SIK3 gene. Published research associates it with triacylglyceride levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10892063 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10892063 come from?

GWAS Catalog, Nature communications 2022, PMID:35945198. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triacylglyceride levels (rs10892063). MyGeneLog™. https://www.mygenelog.com/variants/rs10892063

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