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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 14,296 European ancestry individuals; replicated in 5,698 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0783 higher (95% confidence interval 0.053-0.104); p = 2 × 10−9.
How common The T allele had a frequency of about 82% in the people studied.
Where it sits Chromosome 11, band 11q23.2 — between genes, 1.6 kb from NNMT.
What each result means
C/CNo copy of the version the research linked to 1-methylnicotinamide levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to 1-methylnicotinamide levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to 1-methylnicotinamide levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature medicine · 2022 · PMID 36357675 · open access
Questions about rs10891647
What is rs10891647?
rs10891647 is a single position in the genome, in or near the near NNMT gene. Published research associates it with 1-methylnicotinamide levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10891647 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10891647 come from?
GWAS Catalog, Nature medicine 2022, PMID:36357675. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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